Wani sabon bincike mai taken "Amfani da Pix-2-Pix GAN don Zurfafa Ilmi-Tsashen Gabaɗayan Jiki PSMA PET/CT Gyaran Jiki" an buga kwanan nan a Juzu'i na 15 na Oncotarget akan Mayu 7, 2024.
Bayyanar radiation daga binciken PET/CT na jeri a cikin bibiyar marasa lafiyar oncology abin damuwa ne. A cikin wannan binciken na baya-bayan nan, ƙungiyar masu bincike ciki har da Kevin C. Ma, Esther Mena, Liza Lindenberg, Nathan S. Lay, Phillip Eclarinal, Deborah E. Citrin, Peter A. Pinto, Bradford J. Wood, William L. Dahut, James L. Gulley, Ravi A. Madan, Peter L. Choyke, Ismail Baris Turkbey, da Stephanie A. Harmon daga Cibiyar Ciwon daji ta Kasa a Cibiyoyin Kiwon Lafiya na Kasa sun gabatar da kayan aikin fasaha na wucin gadi (AI). Wannan kayan aikin yana nufin samar da hotunan PET da aka gyara (AC-PET) daga hotunan PET da ba a gyara ba (NAC-PET), mai yuwuwar rage buƙatun CT sikanin ƙananan allurai.
"Hotunan PET da aka samar da Ai suna da yuwuwar asibiti don rage buƙatar gyare-gyaren attenuation akan CT scans yayin da ake adana alamomi masu ƙididdigewa da ingancin hoto ga masu cutar kansar prostate."
Hanyoyi: Algorithm na ilmantarwa mai zurfi bisa 2D Pix-2-Pix gine-ginen cibiyar sadarwa ta gaba (GAN) an ɓullo da shi bisa haɗe-haɗe da hotuna AC-PET da NAC-PET. 18F-DCFPyL PSMA (Prostate-specific membrane antigen) PET-CT binciken na 302 marasa lafiya da ciwon gurguwar prostate an raba su zuwa horo, tabbatarwa, da ƙungiyoyin gwaji (n 183, 60, da 59, bi da bi). An horar da samfurin ta amfani da daidaitattun dabaru guda biyu: Standard Uptake Value (SUV) tushen da SUV-NYUL. An ƙididdige aikin dubawa a kwance ta amfani da daidaitaccen kuskuren murabba'in murabba'i (NMSE), ma'anar cikakken kuskure (MAE), ma'anar kamanni (SSIM) da ƙimar sigina-zuwa-amo (PSNR). Likitan likitancin nukiliya zai yi nazarin matakin rauni na yanki mai sha'awa. An ƙididdige alamun SUV ta amfani da haɗin haɗin haɗin-ƙungiya (ICC), ƙimar maimaitawa (RC), da samfuran tasirin tasiri na layi.
Sakamako:A cikin ƙungiyar gwaji mai zaman kanta, matsakaicin NMSE, MAE, SSIM, da PSNR sun kasance 13.26%, 3.59%, 0.891, da 26.82, bi da bi. ICC na SUVmax da SUVmean sun kasance 0.88 da 0.89, yana nuna alaƙa mai ƙarfi tsakanin alamomin hoto na asali da AI da aka samar. Abubuwa irin su wurin rauni, yawa (raka'o'in Hounsfield), da kuma raunin raunin an gano su don tasiri kuskuren dangi a cikin ma'aunin SUV da aka samar (duk p <0.05).
"AC-PET wanda samfurin Pix-2-Pix GAN ya samar yana nuna ma'aunin SUV wanda ya yi daidai da ainihin hotunan. Hotunan PET da aka kirkira na AI suna ba da kyakkyawar damar asibiti don rage wajabcin CT scans don gyara attenuation yayin kiyaye alamomin adadi da ingancin hoto."
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Kamar yadda muka sani, ci gaban masana'antar hoto na likitanci ba shi da bambanci da haɓakar kayan aikin likitanci - injectors masu bambanta da masu amfani da su - waɗanda ake amfani da su sosai a cikin wannan fagen. A kasar Sin, wadda ta shahara wajen masana'antar kere-kere, akwai masana'anta da dama da suka shahara a gida da waje wajen kera kayayyakin aikin likitanci, wadanda suka hada da.LnkMed. Tun lokacin da aka kafa shi, LnkMed yana mai da hankali kan fagen injectors masu matsakaicin matsa lamba. Ƙungiyar injiniya ta LnkMed tana jagorancin Ph.D. tare da fiye da shekaru goma na gwaninta kuma yana da zurfi cikin bincike da ci gaba. A karkashin jagorancinsa, daCT allurar kai guda ɗaya,CT biyu kai allura,MRI bambanci wakili injector, kumaAngiography high-matsa lamba bambanci wakili injectoran tsara su tare da waɗannan fasalulluka: jiki mai ƙarfi da ƙaƙƙarfan jiki, mai sauƙin aiki mai dacewa da fasaha, cikakkun ayyuka, babban aminci, da ƙira mai dorewa. Hakanan zamu iya samar da sirinji da bututun da suka dace da waɗancan shahararrun samfuran CT, MRI, DSA injectors Tare da halayensu na gaskiya da ƙarfin ƙwararru, duk ma'aikatan LnkMed suna gayyatar ku da gaske don ku zo ku bincika ƙarin kasuwanni tare.
Lokacin aikawa: Mayu-14-2024
